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Article

Quantitative genetic variation in body size of mice from new mutations.

Genetics - 1 Jul 1992

Keightley P D, Hill W G

Abstract excerpt

To measure the amount of new genetic variation in 6-week weight of mice arising each generation from mutation, selection lines derived from an initially inbred strain were maintained for 25 generations. An analysis using an animal model with restricted maximum likelihood was applied to estimate a mutational genetic component of variance for the infinitesimal model of many genes of small effect. Assuming that the...

Topics

Animals
Body Constitution
Female
Genetic Variation
Male
Mice
Mice, Inbred C3H
Models, Genetic
Mutation
Selection, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1628812
DOI: 10.1093/genetics/131.3.693
PMCID: PMC1205040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1628812-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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