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Article

A pleiotropic nonadditive model of variation in quantitative traits.

Genetics - 1 Nov 1994

Caballero A, Keightley P D

Abstract excerpt

A model of mutation-selection-drift balance incorporating pleiotropic and dominance effects of new mutations on quantitative traits and fitness is investigated and used to predict the amount and nature of genetic variation maintained in segregating populations. The model is based on recent information on the joint distribution of mutant effects on bristle traits and fitness in Drosophila melanogaster from...

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Identifiers

PMID: 7851783
DOI: 10.1093/genetics/138.3.883
PMCID: PMC1206236

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