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Article

The role of complement component C3b and its receptors in sperm-oocyte interaction.

1 Nov 1993

Abstract excerpt

Previous studies have shown that human sperm that have undergone the acrosome reaction express a unique tissue-specific variant of the complement component 3 (C3)-binding molecule membrane cofactor protein (MCP, CD46) and that damaged or dead sperm activate the alternative pathway of complement and bind C3 catabolites. In this study we provide evidence that MCP on sperm that have undergone the acrosome reaction...

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Identifiers

PMID: 8234255
DOI: 10.1073/pnas.90.21.10051

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