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How hormones may modulate human skin pigmentation in melasma: An in vitro perspective

18 Mar 2019

Abstract excerpt

Melasma is a common acquired hyperpigmentary disorder occurring primarily in photo-exposed areas and mainly affecting women of childbearing age. To decipher the role of sex hormones in melasma, this viewpoint reviews the effects of sex hormones on cutaneous cells cultured in monolayers, in coculture, in 3D models and explants in the presence or the absence of UV. The data show that sex steroid hormones,...

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PMID: 30883945
DOI: 10.1111/exd.13915

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