Article
Role of the conserved Lys-X-Gly-Gly sequence at the ADP-glucose-binding site in Escherichia coli glycogen synthase.
The Journal of biological chemistry - 15 Nov 1993
Furukawa K, Tagaya M, Tanizawa K, Fukui T
Abstract excerpt
Although bacterial and mammalian glycogen synthases differ in the primary structure and specificity for glucosyl donor, lysyl residues identified at their substrate-binding sites by affinity labeling are present in a conserved tetrapeptide sequence, Lys-X-Gly-Gly, where X is a residue not conserv...
Topics
- Adenosine Diphosphate Glucose
- Affinity Labels
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Catalysis
- Conserved Sequence
- DNA Primers
- Escherichia coli
- Glycine
- Glycogen Synthase
- Humans
- Kinetics
- Lysine
- Molecular Sequence Data
- Mutation