Two global regulatory systems (Crp and Arc) control the cobalamin/propanediol regulon of Salmonella typhimurium.

doi:10.1128/jb.175.22.7200-7208.1993

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Article

Two global regulatory systems (Crp and Arc) control the cobalamin/propanediol regulon of Salmonella typhimurium.

Journal of bacteriology - 1 Nov 1993

Ailion M, Bobik T A, Roth J R

Abstract excerpt

The genes for cobalamin (vitamin B12) biosynthesis (cob) are coregulated with genes for degradation of propanediol (pdu). Both the cob and pdu operons are induced by propanediol by means of a positive regulatory protein, PocR. This coregulation of a synthetic and a degradative pathway reflects the fact that vitamin B12 is a required cofactor for the first enzyme in propanediol breakdown. The cob/pdu regulon is...

Topics

Aerobiosis
Anaerobiosis
Bacterial Proteins
Cyclic AMP
DNA-Binding Proteins
Fumarates
Gene Expression Regulation, Bacterial
Genes, Bacterial
Genotype
Models, Genetic
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Operon

Propylene Glycols

Pyruvates

Regulon

Salmonella typhimurium

Trans-Activators

Transcription, Genetic

Source

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Identifiers

PMID: 8226666
DOI: 10.1128/jb.175.22.7200-7208.1993
PMCID: PMC206861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8226666-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Two global regulatory systems (Crp and Arc) control the cobalamin/propanediol regulon of Salmonella typhimurium.PMID 8226666Read ↗

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