Article
Molecular characterization of PrpR, the transcriptional activator of propionate catabolism in Corynebacterium glutamicum.
Journal of biotechnology - 31 May 2012
Plassmeier Jens, Persicke Marcus, Pühler Alfred, Sterthoff Charlott, Rückert Christian, Kalinowski Jörn
Abstract excerpt
The 2-methylcitrate cycle is used to metabolize propionate in Corynebacterium glutamicum. The regulator, PrpR (Cg0800), of the prpDBC2 operon was identified and characterized. The regulator has no similarities to the up to now known PrpR regulators from other organisms. Growth of a ΔprpR mutant revealed severe growth deficits and a prolonged lag phase if propionate was present in the medium. Transcriptome...
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