Rare HVR1-HCV genotype 1b variants in patients with B non Hodgkin's lymphoma. Comparison with viral sequences detected in cases of lymphoproliferative disorders and B cell compartmentalisation.

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Rare HVR1-HCV genotype 1b variants in patients with B non Hodgkin's lymphoma. Comparison with viral sequences detected in cases of lymphoproliferative disorders and B cell compartmentalisation.

The new microbiologica - 1 Jul 2007

Dettori Stefano, Argentini Claudio, Marcucci Fabrizio, Spada Enea, Chionne Paola, Candido Angela, Madonna Elisabetta, Ciccaglione Anna Rita, Bianco Elvira, Iannitto Emilio, Musto Pellegrino, Liso Vincenzo, De Renzo Amalia, Pagano Livio, Nieddu Grazia, Pulsoni Alessandro, Mele Alfonso, Rapicetta Maria

Abstract excerpt

We compared the E2-HVR1 region in HCV-1b positive B-NHL cases from a multicenter study with sequences from studies related to lymphoproliferative disorders and B cell compartmentalisation. We found rare and unique mutations both in B-NHL isolates and in cases with lymphoproliferative disorders and lymphocyte infection. These rare mutations could have an important effect on HVR1 region and, as a consequence, on...

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PMID: 17802906

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