Article
[Mitochondrial disorders: a classification for the 21st century].
Neurologia (Barcelona, Spain) - 1 Jan 2000
Andreu A L, Gonzalo-Sanz R
Abstract excerpt
Mitochondrial encephalomyopathies were described in the 60's when accumulation of mitochondria were observed in patients with exercise intolerance. The electronic transport chain is located in the mitochondria and forms the oxidative phosphorylation (OXPHOS) system that produces ATP in the cell. The electronic transport chain is coded by two different genomes, nuclear and mitochondrial, with different genetic...
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