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Article

The effect of prenatal diazepam exposure on TNF-alpha production by rat splenocytes.

Agents and actions - 1 Mar 1993

Schreiber A A, Frei K, Lichtensteiger W, Schlumpf M

Abstract excerpt

Prenatal exposure to diazepam and other benzodiazepines (BDZ) has been found to result in a marked reduction of T-lymphocyte proliferation during postnatal development of rats. In search for pathogenic changes underlying this effect, we investigated the mitogen lipopolysaccharide (LPS) and concanavalin A (ConA) stimulated release of tumour necrosis factor (TNF)-alpha by mixed splenocytes of male offspring from...

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PMID: 8213353
DOI: 10.1007/BF01976219

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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