Article
Invasion of experimental rat brain tumor: early morphological changes following microinjection of C6 glioma cells.
Acta neuropathologica - 1 Jan 1993
Nagano N, Sasaki H, Aoyagi M, Hirakawa K
Abstract excerpt
We present morphological data of the early stage of tumor invasion in the central nervous system. C6 rat glioma cells were injected into the caudate-putamen of rat brain using glass micropipettes to minimize traumatic reactions. Four days after the inoculation, we examined the tumor-brain interfa...
Topics
- Animals
- Astrocytes
- Axons
- Brain Neoplasms
- Bromodeoxyuridine
- Cell Transplantation
- Glioma
- Immunohistochemistry
- Male
- Microinjections
- Microscopy, Electron
- Myelin Sheath
- Neoplasm Invasiveness
- Neoplasm Transplantation
- Phenotype
- Rats
- Rats, Wistar
- Tumor Cells, Cultured