Article
Analysis of DNA changes in the LPL gene in patients with familial combined hyperlipidemia.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Aug 1994
Gagné E, Genest J, Zhang H, Clarke L A, Hayden M R
Abstract excerpt
Familial combined hyperlipidemia (FCHL) is a common lipid disorder characterized by an increase in cholesterol and/or triglyceride levels in multiple individuals of the same family. Prior reports document a decreased activity of lipoprotein lipase (LPL) in FCHL, and studies of the role of LPL in...
Topics
- Adult
- Aged
- Amino Acid Sequence
- Amino Acids
- Base Sequence
- DNA
- Exons
- Humans
- Hyperlipidemia, Familial Combined
- Lipoprotein Lipase
- Middle Aged
- Molecular Sequence Data
- Mutation
- Phenotype