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Article

Tolerance to ethanol hypothermia in HOT and COLD mice.

Alcoholism, clinical and experimental research - 1 Feb 1994

Crabbe J C

Abstract excerpt

COLD and HOT mice have been selected to be sensitive or resistant, respectively, to the acute hypothermic effect of ethanol. Previous studies have found HOT mice to be relatively resistant to the development of tolerance to this effect, whereas COLD mice readily develop tolerance. By administering several doses of ethanol and recording multiple postdrug temperatures, in the current study we equated the selected...

Topics

Animals
Body Temperature Regulation
Dose-Response Relationship, Drug
Drug Tolerance
Ethanol
Female
Genotype
Male
Mice
Mice, Inbred Strains

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8198225
DOI: 10.1111/j.1530-0277.1994.tb00878.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8198225-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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