Article
Entamoeba histolytica: electron-dense granule secretion, collagenase activity and virulence are altered in the cytoskeleton mutant BG-3.
Molecular microbiology - 1 Feb 1994
Serrano J J, de la Garza M, Moreno M A, Tovar R, León G, Tsutsumi V, Muñoz M L
Abstract excerpt
HM-1:IMSS, a pathogenic strain of Entamoeba histolytica, and its mutant BG-3, identified by resistance to cytochalasin D, were tested for their capacity to: (i) secrete electron-dense granules; (ii) adhere and digest native type I collagen gels; and (iii) produce liver abscesses in new-born hamst...
Topics
- Animals
- Animals, Newborn
- Cell Adhesion
- Collagen
- Collagenases
- Cricetinae
- Cytochalasin D
- Cytoplasmic Granules
- Cytoskeleton
- Drug Resistance
- Entamoeba histolytica
- Liver Abscess, Amebic
- Mesocricetus
- Mutation
- Protozoan Proteins
- Virulence