Chromosomal alterations of Candida albicans are associated with the gain and loss of assimilating functions.

Abstract excerpt

We have demonstrated that a normal laboratory strain of Candida albicans spontaneously produces mutants which acquire the ability to assimilate certain carbon sources that are not utilized by the parental strain. The examination of mutants acquiring the ability to utilize either sorbose or D-arabinose revealed a few additional phenotypic changes, including the gain and loss of the capacity to assimilate other...

Topics

• Arabinose
• Candida albicans
• Chromosome Aberrations
• Chromosomes, Fungal
• Electrophoresis
• Genetic Variation
• Karyotyping
• Morphogenesis
• Mutation
• Sorbose