Article
Effect of the major repeat sequence on chromosome loss in Candida albicans.
Eukaryotic cell - 1 Apr 2005
Lephart Paul R, Chibana Hiroji, Magee Paul T
Abstract excerpt
The major repeat sequence (MRS) is found at least once on all but one chromosome in Candida albicans, but as yet it has no known relation to the phenotype. The MRS affects karyotypic variation by serving as a hot spot for chromosome translocation and by expanding and contracting internal repeats, thereby changing chromosome length. Thus, MRSs on different chromosomes and those on chromosome homologues can differ...
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