Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MHC evolution and development of a recognition system.

Annals of the New York Academy of Sciences - 15 Apr 1994

Ohno S

Abstract excerpt

The unrestricted viability of allophenic mice shows that MHC-different cell lines have no problem engaging in organogenesis together. Thus, outside of the immune system, mammals appear to have no self-non-self discrimination mechanism based on polymorphic and ubiquitously expressed class I MHC antigens. Here, it should be pointed out that even within the immune system, certain responses require no self-non-self...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Biological Evolution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chick Embryo

Share to Histocompatibility Antigens Class I

Share to Major Histocompatibility Complex

Share to Molecular Sequence Data

Source

Identifiers

PMID: 8192327
DOI: 10.1111/j.1749-6632.1994.tb33558.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MHC evolution and development of a recognition system.PMID 8192327Read ↗

The evolution of alloimmunity and the genesis of adaptive immunity.Semantic proximity Read ↗

Coevolution of T‐cell receptors with MHC and non‐ MHC ligandsSemantic proximity Read ↗

Development of Immune System: Conservation of Species IdentitySemantic proximity Read ↗

Immunological Diversity Is a Cornerstone of Organismal Defense and Allorecognition across Metazoa.Semantic proximity Read ↗

The Nature of Selection on the Major Histocompatibility Complex.Semantic proximity Read ↗

Activation of self-reactive B cells and autoimmune diseases.Semantic proximity Read ↗

Germline and somatic diversification of immune recognition elements in Metazoa.Semantic proximity Read ↗

Ecoimmunity: immune tolerance by symmetric co-evolution.Semantic proximity Read ↗

Calibrating Human Immunity in the Context of Advanced Microbial Evolution and Self-CamouflagingSemantic proximity Read ↗

The evolution of powerful yet perilous immune systemsSemantic proximity Read ↗

[Immunity in the evolution of multicellular animals].Semantic proximity Read ↗

New take on comparative immunology: relevance to immunotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.