Mutation load and mutation-selection-balance in quantitative genetic traits.

doi:10.1007/BF00163878

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Article

Mutation load and mutation-selection-balance in quantitative genetic traits.

Journal of mathematical biology - 1 Jan 1994

Bürger R, Hofbauer J

Abstract excerpt

Haldane (1937) showed that the reduction of equilibrium mean fitness in an infinite population due to recurrent deleterious mutations depends only on the mutation rate but not on the harmfulness of mutants. His analysis, as well as more recent ones (cf. Crow 1970), ignored back mutation. The purp...

Topics

Alleles
Diploidy
Mathematics
Models, Genetic
Mutation
Selection, Genetic

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