Article
Expression of tumor-associated protein variants in chemically induced rat hepatomas and transformed rat liver cell lines determined by two-dimensional electrophoresis.
Electrophoresis - 1 Jan 2000
Zeindl-Eberhart E, Jungblut P, Rabes H M
Abstract excerpt
High resolution two-dimensional electrophoresis (2-DE), using the rat liver as a model, was applied to study hepatocarcinogenesis induced by different chemical carcinogens. Several tumor-associated protein variants were detected by 2-DE in chemically induced rat hepatomas and transformed rat live...
Topics
- Aldehyde Reductase
- Amino Acid Sequence
- Animals
- Cell Line, Transformed
- Electrophoresis, Gel, Two-Dimensional
- Genetic Variation
- Indicators and Reagents
- Isoelectric Focusing
- Lens, Crystalline
- Liver
- Liver Neoplasms, Experimental
- Methylnitrosourea
- Molecular Sequence Data
- Neoplasm Proteins
- Peptide Fragments
- Peptide Mapping
- Phosphorus Radioisotopes
- Protein Biosynthesis