Article
Morphine induced, behavioural, biochemical and immunological correlations.
Annali dell'Istituto superiore di sanita - 1 Jan 1993
Nyazema N Z
Abstract excerpt
Tolerance and dependence on morphine appear more or less simultaneously. Evidence has accumulated that addiction leads to depressed immune function and seem to suggest that dependence is under genetic influence. Morphine and related substances of abuse open perspective on ways to investigate the basic mechanisms related to their cellular and systemic effects.
Topics
- Animals
- Drug Tolerance
- Genetic Predisposition to Disease
- Humans
- Immunologic Deficiency Syndromes
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Morphine
- Morphine Dependence
- Neuroimmunomodulation
- Rats