Article
Opioids and corticosteroids involvement in the regulation of the neocortical spindling episodes in DBA/2J mice.
Annali dell'Istituto superiore di sanita - 1 Jan 1993
Capasso A, Di Giannuario A, Loizzo A, Palazzesi S, Cutrufo C, Pieretti S, Sorrentino L
Abstract excerpt
The present study examined the effects of dexamethasone and RU-38486 on the spike-and-wave spindling episodes (S&W) which can be spontaneously recorded in the electroencephalogram (EEG) of DBA/2J mice. Our data indicated that dexamethasone (1-10-100 micrograms/kg, ip) in a time- and dose-related...
Topics
- Adrenal Cortex
- Animals
- Cerebral Cortex
- Corticosterone
- Cycloheximide
- Dexamethasone
- Disease Models, Animal
- Disease Susceptibility
- Electroencephalography
- Epilepsy
- Genetic Predisposition to Disease
- Male
- Mice
- Mice, Inbred DBA
- Mifepristone
- Morphine
- Naltrexone