Article
Cellular expression of the beige mouse mutation and its correction in hybrids with control human fibroblasts.
In vitro cellular & developmental biology. Animal - 1 Nov 1993
Gow J B, Lainwala S, Lyerla T A
Abstract excerpt
Fibroblasts from a beige mouse (C57BL/6J; bgJ bgJ) have been established and maintained in culture for more than 3 yr. At early passages, the mutant cells were distinguishable from C57BL/6J control mouse fibroblasts at the ultrastructural level by the presence of enlarged cytoplasmic granules. Af...
Topics
- Acid Phosphatase
- Animals
- Cell Line
- Cytoplasmic Granules
- Fibroblasts
- Humans
- Hybrid Cells
- Karyotyping
- Lysosomes
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mutation
- Phenotype