Article
Detection of quantitative trait loci from frequency changes of marker alleles under selection.
Genetical research - 1 Dec 1993
Keightley P D, Bulfield G
Abstract excerpt
A method was developed to estimate effects of quantitative trait loci (QTL) by maximum likelihood using information from changes of gene frequency at marker loci under selection, assuming an additive model of complete linkage between markers and QTL. The method was applied to data from 16 molecular and coat colour marker loci in mouse lines derived from the F2 of two inbred strains which were divergently selected...
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