Article
Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 1994
Hoyland J A, Freemont A J, Sharpe P T
Abstract excerpt
The cytokine interleukin-6 (IL-6) is considered an important regulator of bone cell function and may play a central role in bone disease states characterized by increased bone remodeling, such as Paget's disease. Indeed, recent in vitro data suggest that IL-6 may be an autocrine/paracrine factor...
Topics
- Bone Remodeling
- Bone and Bones
- CCAAT-Enhancer-Binding Proteins
- DNA-Binding Proteins
- Gene Expression
- Humans
- In Situ Hybridization
- Interleukin-6
- Nuclear Proteins
- Osteitis Deformans
- Osteoarthritis
- Osteoblasts
- Osteoclasts
- Phenotype
- RNA, Messenger
- Receptors, Interleukin
- Receptors, Interleukin-6
- Respirovirus