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Article

HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro.

Journal of leukocyte biology - 1 Apr 1994

Dürrbaum-Landmann I, Kaltenhäuser E, Flad H D, Ernst M

Abstract excerpt

We investigated the effect of human immunodeficiency virus type 1 (HIV-1) recombinant gp120 (rec.gp120) on phenotype and function of cultured monocytes. Rec.gp120 significantly reduced the accessory function of monocytes to stimulate autologous lymphocytes with anti-CD3, the Fc receptor-mediated chemiluminescence of monocytes, and the expression of CD4 and Fc receptor I/II, while the expression of the monocyte...

Topics

Antigen Presentation
CD4 Antigens
HIV Envelope Protein gp120
HIV Infections
Humans
In Vitro Techniques
Interleukin-6
Luminescent Measurements
Lymphocyte Activation
Monocytes
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Fc

Tuberculin

Source

Identifiers

PMID: 8145026
DOI: 10.1002/jlb.55.4.545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8145026-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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