Cytokines and oncogenes in cellular interactions of rheumatoid arthritis.

doi:10.1002/stem.5530120114

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Article

Cytokines and oncogenes in cellular interactions of rheumatoid arthritis.

Stem cells (Dayton, Ohio) - 1 Jan 1994

Keyszer G M, Heer A H, Gay S

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic systemic disorder of unknown etiology. Most of its debilitation sequelae are derived from progressive destruction of joints. The affected joints exhibit inflammation, abnormal immune responses and synovial hyperplasia. Although growth factors and cytokines d...

Topics

Arthritis, Rheumatoid
Cell Communication
Cytokines
Enzyme Induction
Fibroblasts
Gene Expression Regulation
Humans
Macrophages
Metalloendopeptidases
Phenotype
Proto-Oncogenes
Synovial Membrane

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