Article
Nephrogenic diabetes insipidus: causes revealed.
Hospital practice (Office ed.) - 15 Mar 1994
Holtzman E J, Ausiello D A
Abstract excerpt
In congenital NDI, the failure of the renal tubules to respond to antidiuretic hormone is caused by mutation of the arginine vasopressin receptor gene. Two dozen different mutations have been identified to date--all with the same clinical consequences. Several causes of acquired NDI, of which lit...
Topics
- Arginine Vasopressin
- Base Sequence
- Chromosome Mapping
- DNA
- Demeclocycline
- Diabetes Insipidus
- Female
- Genetic Linkage
- Heterozygote
- Humans
- Lithium
- Male
- Molecular Sequence Data
- Mutation
- Pedigree
- Receptors, Vasopressin
- Signal Transduction
- X Chromosome