Article
Characterization of the alloreactivity and anti-leukemia reactivity of cord blood mononuclear cells.
Bone marrow transplantation - 1 Mar 1995
Keever C A, Abu-Hajir M, Graf W, McFadden P, Prichard P, O'Brien J, Flomenberg N
Abstract excerpt
It has been suggested that cord blood T cells may be less able to mediate GVHD than marrow-derived T cells due to their naive status. A decreased potential for GVHD may be advantageous for allogeneic transplant, but this benefit might be counteracted by loss of the GVHD associated graft-versus-le...
Topics
- Adult
- Antigens, CD
- CD4-CD8 Ratio
- Cell Adhesion Molecules
- Cells, Cultured
- Female
- Fetal Blood
- Humans
- Immunophenotyping
- Interleukin-2
- Killer Cells, Natural
- Lymphocyte Activation
- Lymphocyte Culture Test, Mixed
- Phenotype
- T-Lymphocytes
- T-Lymphocytes, Cytotoxic
