Article
Glycophorin variants and Plasmodium falciparum: protective effect of the Dantu phenotype in vitro.
Human genetics - 1 Feb 1994
Field S P, Hempelmann E, Mendelow B V, Fleming A F
Abstract excerpt
Experimental work was carried out to establish the growth characteristics of Plasmodium falciparum in an in vitro culture system using cells with the Dantu, Henshaw and S-s-U- blood-group variants. A flow cytometric technique, using the dye thiazole orange, was adapted for use on the Epics Profile II flow cytometer to count the parasites. This was performed at 24, 48 and 72 h. The ability of the parasites to grow...
Topics
- Animals
- Black People
- Cells, Cultured
- Erythrocytes
- Flow Cytometry
- Glycophorins
- Humans
- Phenotype
- Plasmodium falciparum
- Rh-Hr Blood-Group System