Article
Problem hepatitis viruses: the mutants.
The American journal of medicine - 17 Jan 1994
Koff R S
Abstract excerpt
Genetic variations in the known human hepatitis viruses are probably the result (a) of high viral replication rates and poor or absent proofreading ability intrinsic to RNA viruses (HAV, HCV, HDV, HEV) and (b) to a DNA virus (HBV) that uses a reverse-transcription mechanism for genomic replication. Nucleotide substitutions, deletions, duplications, insertions, and rearrangements resulting in amino acid changes...
Topics
- Hepatitis Viruses
- Humans
- Mutation