Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun.
Oncogene - 1 Mar 1994
Kerppola T K, Curran T
Abstract excerpt
The c-maf proto-oncogene and the neural retina specific gene nrl encode members of a new bZIP protein subfamily. We have examined the dimerization and DNA binding properties of this new protein family using polypeptides encompassing the leucine zipper and basic regions. Purified polypeptides bound specifically to the AP-1 and CRE sites as well as to variants of the AP-1 site. Maf and Nrl were also able to form...
Topics
Amino Acid Sequence
Base Sequence
Basic-Leucine Zipper Transcription Factors
DNA
DNA-Binding Proteins
Eye Proteins
Humans
Leucine Zippers
Molecular Sequence Data
Mutation
Protein Binding
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-fos
Proto-Oncogene Proteins c-jun
Proto-Oncogene Proteins c-maf
Sequence Homology, Amino Acid
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Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun.PMID 8108109Read ↗
