Article
T cells involved in psoriasis vulgaris belong to the Th1 subset.
The Journal of investigative dermatology - 1 Feb 1994
Schlaak J F, Buslau M, Jochum W, Hermann E, Girndt M, Gallati H, Meyer zum Büschenfelde K H, Fleischer B
Abstract excerpt
Although the pathogenesis of psoriasis vulgaris is still unknown, several characteristics point to an immunologically mediated process. Epidermal psoriatic lesions are characterized by a hyperproliferation of keratinocytes and an infiltration of T lymphocytes and granulocytes. Because the former...
Topics
- Adult
- Aged
- Aged, 80 and over
- Arthritis, Psoriatic
- Base Sequence
- Biopsy
- CD4 Antigens
- CD8 Antigens
- Cells, Cultured
- Cytokines
- Female
- Humans
- Interferon-gamma
- Interleukin-10
- Interleukin-2
- Interleukin-4
- Male
- Middle Aged