Article
T cells involved in psoriasis vulgaris belong to the Th1 subset.
The Journal of investigative dermatology - 1 Feb 1994
Schlaak J F, Buslau M, Jochum W, Hermann E, Girndt M, Gallati H, Meyer zum Büschenfelde K H, Fleischer B
Abstract excerpt
Although the pathogenesis of psoriasis vulgaris is still unknown, several characteristics point to an immunologically mediated process. Epidermal psoriatic lesions are characterized by a hyperproliferation of keratinocytes and an infiltration of T lymphocytes and granulocytes. Because the former may be mediated in part by lymphokines secreted by T cells, we have focused our interest on the in vivo and in vitro...
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