Article
Role of phase variation of type 1 fimbriae in a uropathogenic Escherichia coli cystitis isolate during urinary tract infection.
Infection and immunity - 1 Feb 2006
Snyder Jennifer A, Lloyd Amanda L, Lockatell C Virginia, Johnson David E, Mobley Harry L T
Abstract excerpt
Type 1 fimbrial phase-locked mutants of uropathogenic Escherichia coli cystitis isolate F11 were used to assess the role of the invertible element during urinary tract infection. Compared to the wild type, the phase-locked off mutant was attenuated, and constitutive production of type 1 fimbriae by the phase-locked on mutant did not provide a competitive advantage.
Topics
- Animals
- Colony Count, Microbial
- Cystitis
- Escherichia coli
- Escherichia coli Infections
- Escherichia coli Proteins
- Female
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Humans
- Kidney
- Mice
- Mice, Inbred CBA
- Mutation