Article
Reevaluation of the chromosome 4q candidate region for early onset periodontitis.
Human genetics - 1 Jun 1993
Hart T C, Marazita M L, McCanna K M, Schenkein H A, Diehl S R
Abstract excerpt
Evidence of linkage (lod = 3.1, theta = 0.05) was reported previously in one large kindred (the Brandywine genetic isolate) for an autosomal dominant form of early onset periodontitis (EOP) with a protein polymorphism in the vitamin D binding protein (GC) located on chromosome 4q12-q13. To evaluate the generality of this finding, 19 unrelated families (228 individuals), each with two or more EOP affected...
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