Reevaluation of the chromosome 4q candidate region for early onset periodontitis.

doi:10.1007/BF00217764

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Article

Reevaluation of the chromosome 4q candidate region for early onset periodontitis.

Human genetics - 1 Jun 1993

Hart T C, Marazita M L, McCanna K M, Schenkein H A, Diehl S R

Abstract excerpt

Evidence of linkage (lod = 3.1, theta = 0.05) was reported previously in one large kindred (the Brandywine genetic isolate) for an autosomal dominant form of early onset periodontitis (EOP) with a protein polymorphism in the vitamin D binding protein (GC) located on chromosome 4q12-q13. To evalua...

Topics

Adolescent
Adult
Aggressive Periodontitis
Chi-Square Distribution
Child
Chromosome Mapping
Chromosomes, Human, Pair 4
Genetic Linkage
Genetic Variation
Humans
Likelihood Functions
Lod Score
Polymorphism, Restriction Fragment Length
Reproducibility of Results

Source

Open in PubMed

Identifiers

PMID: 8100208
DOI: 10.1007/BF00217764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8100208-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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