Article
Genetic linkage of the dentinogenesis imperfecta type III locus to chromosome 4q.
Journal of dental research - 1 Jun 1999
MacDougall M, Jeffords L G, Gu T T, Knight C B, Frei G, Reus B E, Otterud B, Leppert M, Leach R J
Abstract excerpt
Dentinogenesis imperfecta type III (DGI-III) is an autosomal-dominant disorder of dentin formation which appears in a tri-racial southern Maryland population known as the "Brandywine isolate". This disease has suggestive evidence of linkage to the long arm of human chromosome 4 (LOD score of 2.0) in a family presenting with both juvenile periodontitis and DGI-III. The purpose of this study was to screen a family...
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