Association of HLA-A24 with complete beta-cell destruction in IDDM.

doi:10.2337/diab.42.7.1086

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Article

Association of HLA-A24 with complete beta-cell destruction in IDDM.

Diabetes - 1 Jul 1993

Nakanishi K, Kobayashi T, Murase T, Nakatsuji T, Inoko H, Tsuji K, Kosaka K

Abstract excerpt

A sensitive C-peptide immunoreactivity radioimmunoassay demonstrated the presence of subtle, but definite residual beta-cell function in patients with IDDM of long duration. Although HLA antigens are known to influence susceptibility to IDDM, their contribution to the extent of pancreatic beta-cell destruction has not yet been examined extensively. We studied the relationship between residual beta-cell function...

Topics

Adolescent
Adult
Alleles
Base Sequence
C-Peptide
Child
Diabetes Mellitus, Type 1
Female
Glucose Tolerance Test
HLA-A Antigens
HLA-A24 Antigen
HLA-DQ Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histocompatibility Testing

Humans

Islets of Langerhans

Male

Middle Aged

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 8099884
DOI: 10.2337/diab.42.7.1086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8099884-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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