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Article

Genetic basis of human complement C8 beta deficiency.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1993

Kaufmann T, Hänsch G, Rittner C, Späth P, Tedesco F, Schneider P M

Abstract excerpt

The eighth component of human complement (C8) is a serum protein consisting of three chains (alpha, beta, and gamma) and encoded by three different genes, C8A, C8B, and C8G. C8A and C8B are closely linked on chromosome 1p, whereas C8G is located on chromosome 9q. In the serum the beta subunit is non-covalently bound to the disulfide-linked alpha-gamma subunit. Patients with C8 beta deficiency suffer from...

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PMID: 8098723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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