Genetic basis of human complement C8 beta deficiency.

Article

Genetic basis of human complement C8 beta deficiency.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1993

Kaufmann T, Hänsch G, Rittner C, Späth P, Tedesco F, Schneider P M

Abstract excerpt

The eighth component of human complement (C8) is a serum protein consisting of three chains (alpha, beta, and gamma) and encoded by three different genes, C8A, C8B, and C8G. C8A and C8B are closely linked on chromosome 1p, whereas C8G is located on chromosome 9q. In the serum the beta subunit is...

Topics

Base Sequence
Codon
Complement C8
Exons
Humans
Molecular Sequence Data
Mutation
Pedigree
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.