Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The eighth component of human complement: molecular basis of C8A (C81) polymorphism.

Human genetics - 1 Sept 1995

Zhang L, Rittner C, Sodetz J M, Schneider P M, Kaufmann T

Abstract excerpt

Using an exon-specific polymerase chain reaction (PCR) followed by direct DNA sequence analysis we have analyzed the polymorphism of the alpha-chain of the eighth component of human complement (C8) at the DNA level. We found that two common alleles, C8A*A and C8A*B, are characterized by the substitution of a single amino acid (Gln to Lys), which is caused by a point mutation of a single nucleotide (C to A) in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 7649542
DOI: 10.1007/BF00210407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The eighth component of human complement: molecular basis of C8A (C81) polymorphism.PMID 7649542Read ↗

Human complement C81 (C8 A) polymorphism: detection and segregation of new variants.Semantic proximity Read ↗

[Detecting the DNA polymorphism of human complement component C8A by PCR-SSCP analysis].Semantic proximity Read ↗

Genetic basis of human complement C8 beta deficiency.Semantic proximity Read ↗

Single nucleotide polymorphisms in the human complement C6 and C7 genes.Semantic proximity Read ↗

An investigation of the C4 gene arrangement in ethnic Chinese (Taiwanese).Semantic proximity Read ↗

The human complement C9 gene: structural analysis of the 5' gene region and genetic polymorphism studies.Semantic proximity Read ↗

Molecular epidemiology of C9 deficiency heterozygotes with an Arg95Stop mutation of the C9 gene in Japan.Semantic proximity Read ↗

Typing of the nt343C>T (R95X) allele of the C9 gene by PCR-SSP and the allele frequency of R95X in five ethnic populations.Semantic proximity Read ↗

Polymorphism of human complement component C6: an amino acid substitution (Glu/Ala) within the second thrombospondin repeat differentiates between the two common allotypes C6 A and C6 B.Semantic proximity Read ↗

Characterization, chromosomal localization, and genetic variation of the alpha subunit of porcine eighth component of complement.Semantic proximity Read ↗

DNA polymorphisms of the complement C6 and C7 genes.Semantic proximity Read ↗

A novel human complement component C7 phenotype detected in South Africa and proposed designation of the allele as C7*10.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.