The eighth component of human complement: molecular basis of C8A (C81) polymorphism.

doi:10.1007/BF00210407

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Article

The eighth component of human complement: molecular basis of C8A (C81) polymorphism.

Human genetics - 1 Sept 1995

Zhang L, Rittner C, Sodetz J M, Schneider P M, Kaufmann T

Abstract excerpt

Using an exon-specific polymerase chain reaction (PCR) followed by direct DNA sequence analysis we have analyzed the polymorphism of the alpha-chain of the eighth component of human complement (C8) at the DNA level. We found that two common alleles, C8A*A and C8A*B, are characterized by the subst...

Topics

Alleles
Base Sequence
China
Complement C8
DNA Primers
Exons
Genotype
Humans
Molecular Sequence Data
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic

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