[Molecular analysis of hemophilia A in families of Northeastern Mexico].

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Article

[Molecular analysis of hemophilia A in families of Northeastern Mexico].

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 1 Jan 2000

Rivera-Pérez J A, Rojas-Martínez A, Charles-García F, Barrera-Saldaña H A

Abstract excerpt

We analysed DNA through Southern blot and polymerase chain reaction using blood samples of northeastern Mexican families affected by hemophilia A. Our aim was to identify possible carriers of the mutated gene by indirect detection using the Bcl I polymorphism (RFLP) at intron 18 of the factor VII...

Topics

Alleles
Blotting, Southern
Factor VIII
Female
Genes
Genetic Carrier Screening
Hemophilia A
Humans
Incidence
Introns
Male
Mexico
Pedigree
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 8097893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8097893-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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