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Article

Prenatal diagnosis of leukocyte adhesion deficiency type-1 (five cases from iran with two new mutations).

Iranian journal of allergy, asthma, and immunology - 1 Feb 2014

Esmaeili Behnaz, Ghadami Mohsen, Fazlollahi Mohammad Reza, Niroomanesh Shirin, Atarod Lida, Chavoshzadeh Zahra, Moradi Zeinab, Alizadeh Zahra, Pourpak Zahra

Abstract excerpt

Leukocyte adhesion deficiency type-1(LAD-1) is one of the immunodeficiency autosomal recessive diseases that results from mutation in integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) ITGB2 gene. The aim of this study was to investigate molecular prenatal diagnosis of LAD-1. Four pregnant women with five fetuses (one pregnancy was twin) with clinical and laboratory diagnosis of LAD-1 in their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24338230

Genes

ITGB2
LAD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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