Genetic variation in transforming growth factor alpha: possible association of BamHI polymorphism with bilateral sporadic cleft lip and palate.

doi:10.1007/BF00216150

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Article

Genetic variation in transforming growth factor alpha: possible association of BamHI polymorphism with bilateral sporadic cleft lip and palate.

Human genetics - 1 Aug 1993

Stoll C, Qian J F, Feingold J, Sauvage P, May E

Abstract excerpt

Non-syndromic cleft lip with or without cleft palate (CL/P) is one of the most common birth defects affecting 1/1000 Caucasians. Genetic factors are thought to contribute to the development of this disorder. A significant association between two restriction fragment length polymorphisms, the TGF...

Topics

Child
Child, Preschool
Cleft Lip
Cleft Palate
Deoxyribonuclease BamHI
Genetic Variation
Humans
Infant
Polymorphism, Restriction Fragment Length
Transforming Growth Factor alpha

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