Genetic predisposition in alcoholism: association of the D2 dopamine receptor TaqI B1 RFLP with severe alcoholics.

doi:10.1016/0741-8329(93)90054-r

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Article

Genetic predisposition in alcoholism: association of the D2 dopamine receptor TaqI B1 RFLP with severe alcoholics.

Alcohol (Fayetteville, N.Y.) - 1 Jan 2000

Blum K, Noble E P, Sheridan P J, Montgomery A, Ritchie T, Ozkaragoz T, Fitch R J, Wood R, Finley O, Sadlack F

Abstract excerpt

Previous studies have shown an association of the 3' Taq1 A1 allele of the D2 dopamine receptor (DRD2) gene with severe alcoholism. The recent demonstration of a new polymorphism located closer to the regulatory regions of this gene, permits an associational analysis of these 5' Taq1 B alleles wi...

Topics

Adult
Alcoholism
Alleles
Female
Humans
Male
Middle Aged
Polymorphism, Restriction Fragment Length
Prevalence
Receptors, Dopamine D2
Sex Factors

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