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Article

A multicopy dinucleotide marker that maps close to the spinal muscular atrophy gene.

Genomics - 15 May 1994

Burghes A H, Ingraham S E, McLean M, Thompson T G, McPherson J D, Kote-Jarai Z, Carpten J D, DiDonato C J, Ikeda J E, Surh L

Abstract excerpt

Spinal muscular atrophy (SMA) is a common autosomal recessive disorder resulting in loss of motor neurons. The interval containing the SMA gene has been defined by linkage analysis as 5qcen-D5S435-SMA-D5S557-5qter. We have isolated a new dinucleotide repeat marker, CATT1, that lies between these two closest markers. The marker CATT1 has 16 alleles and is highly polymorphic. The marker can have 1 to 4 (or more)...

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PMID: 8088834
DOI: 10.1006/geno.1994.1282

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