A recombination event occurring within two complex 5q13.1 microsatellite repeat polymorphisms suggests a telomeric mapping of spinal muscular atrophy.

doi:10.1007/BF00210417

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Article

A recombination event occurring within two complex 5q13.1 microsatellite repeat polymorphisms suggests a telomeric mapping of spinal muscular atrophy.

Human genetics - 1 Sept 1995

Yaraghi Z, McLean M D, Roy N, Surh L, Ikeda J E, Korneluk R G, MacKenzie A

Abstract excerpt

The gene for the childhood spinal muscular atrophies (SMAs) has been mapped to 5q13.1. The interval containing the SMA gene has been defined by linkage analysis as 5qcen-D5S629-SMA-D5S557-5qter. We have identified a recombination event within this interval on a type-I SMA chromosome. The recombin...

Topics

Alleles
Base Sequence
Chromosome Mapping
Chromosomes, Artificial, Yeast
Chromosomes, Human, Pair 5
DNA Primers
DNA, Satellite
Genetic Linkage
Genetic Markers
Humans
Infant
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Pedigree

Polymerase Chain Reaction

Polymorphism, Genetic

Recombination, Genetic

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 7649551
DOI: 10.1007/BF00210417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7649551-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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