Article
Tropism for primary monocytes and for monocytoid cell lines are separate features of HIV-1 variants.
Journal of leukocyte biology - 1 Sept 1994
Valentin A, Nilsson K, Asjö B
Abstract excerpt
We have analyzed the phenotype of five human monocytoid cell lines (U-937, THP-1, RC.2A, Mono Mac 6, and DD) and their capacity to support replication of HIV-1 strains with known tropism for T lymphocytes and mononuclear phagocytes. HIV-1 Ba-L, a prototype monocytotropic HIV-1 strain, was unable to establish continuous replication in any of the cell lines used. In contrast, the lymphotropic strain IIIB could...
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