Phenotypic expression of the fused (Fu) gene in chimaeric mice.

doi:10.1017/s001667230003233x

Back to search

Article

Phenotypic expression of the fused (Fu) gene in chimaeric mice.

Genetical research - 1 Jun 1994

Redina O E, Zhelezova A I, Golubitsa A N, Agulnik A I, Ruvinsky A O

Abstract excerpt

The dominant gene Fused (Fu) produces skeletal abnormalities during embryonic development. It was previously shown that C57BL/6 mice contain a suppressor of Fu, which acts after fertilization. Chimaeras were used to study whether this gene would suppress the Fu phenotype after the 8-cell stage of...

Topics

Animals
Blastocyst
Chimera
Female
Gene Expression Regulation
Genes, Dominant
Male
Mice
Mice, Inbred Strains
Phenotype
Suppression, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.