Article
Phenotypic expression of the fused (Fu) gene in chimaeric mice.
Genetical research - 1 Jun 1994
Redina O E, Zhelezova A I, Golubitsa A N, Agulnik A I, Ruvinsky A O
Abstract excerpt
The dominant gene Fused (Fu) produces skeletal abnormalities during embryonic development. It was previously shown that C57BL/6 mice contain a suppressor of Fu, which acts after fertilization. Chimaeras were used to study whether this gene would suppress the Fu phenotype after the 8-cell stage of embryo development. We found no effect of the suppressor gene on Fu phenotype (its degree and frequency of expression)...
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