Article
Trisomy and chromosome size changes in hybrid trypanosomes from a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei.
Molecular and biochemical parasitology - 1 Apr 1992
Gibson W, Garside L, Bailey M
Abstract excerpt
Further analysis of hybrid clones from an experimental cross of Trypanosoma brucei rhodesiense 058 and T. b. brucei 196 shows 2 of the hybrid clones to have DNA contents about 1.5 times parental values. This represents over 40,000 kb of extra DNA. Comparison of the molecular karyotypes of parental and progeny trypanosomes shows that the bulk of the extra DNA constitutes chromosomes greater than 1 Mb in size,...
Topics
- Alleles
- Animals
- Chromosomes
- DNA, Protozoan
- Hybridization, Genetic
- Isocitrate Dehydrogenase
- Isoenzymes
- Karyotyping
- Mice
- Polymorphism, Restriction Fragment Length
- Restriction Mapping
