Article
DQA1*03 subtypes have different associations with DRB1 and DQB1 alleles.
Human immunology - 1 Apr 1994
Fernandez-Viña M A, Falco M, Gao X, Cerna M, Sun Y, Raimondi E, Stastny P
Abstract excerpt
Polymorphisms outside the hypervariable regions of HLA class II alleles that do not affect the peptide-binding site are probably not under selective pressure and could therefore be useful as markers of the evolutionary pathways of the HLA class II haplotypes. We have analyzed such a polymorphism...
Topics
- Alleles
- Base Sequence
- Cell Line
- DNA Primers
- Ethnicity
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Humans
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Polymorphism, Genetic