Article
A novel DRB3 allele (DRB3*0208), a new allelic variant of DRB1*1502 (DRB1*15023) and two new DQB1 (DQB1*03012 and DQB1*0614) alleles.
Tissue antigens - 1 Sept 1998
Hashemi-Tavoularis S, Ouellet S, Sengar D P, Buyse I M
Abstract excerpt
Four novel HLA Class II alleles were identified using CANTYPE reverse hybridization assay. The initial unusual SSO hybridization patterns were confirmed by cloning and sequencing analysis. DRB3*0208 allele is identical to DRB3*0202 except for three nucleotide substitutions (GAT-->AGC) changing co...
Topics
- Alleles
- Base Sequence
- Cloning, Molecular
- Female
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB3 Chains
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Male
- Molecular Sequence Data
- Pedigree
- Sequence Alignment
- Sequence Analysis, DNA