Article
Analysis of T cell receptor variability in fresh tumor-infiltrating lymphocytes from human head and neck cancer.
Japanese journal of cancer research : Gann - 1 Jun 1994
Chikamatsu K, Eura M, Nakano K, Kanzaki Y, Matsuoka H, Masuyama K, Ishikawa T
Abstract excerpt
In this study, we analyzed T cell receptor (TCR) gene rearrangements in tumor-infiltrating lymphocytes (TIL) freshly obtained from 15 patients with head and neck cancer using the reversely transcribed polymerase chain reaction (RT-PCR) method. These TILs showed preferential expression of V alpha 10, V alpha 8 and V alpha 1, detected in 13 (87%), 11 (73%), and 9 cases (60%), respectively. The TCRV beta gene...
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